A study published in the journal Neurobiology of Aging examined brain size and dementia in 239 Swedish residents at age 85. The participants, two-thirds of whom were women, included 104 people with dementia and 135 who were cognitively normal. CT head scans were used to measure total intracranial volume, an indicator of brain size. The scans revealed the presence of white matter lesions, or damage to the brain's connector cells, which are associated with vascular dysfunction.
老年神经生物学》（Neurobiology of Aging）期刊发表的一项研究对239名85岁瑞典居民的脑部大小和痴呆状况进行了检查，其中三分之二为女性，104人患有痴呆症，135人认知正常。研究人员用CT扫描测量他们的颅腔总容量，这是脑部大小的一个指标。扫描结果能显示是否有白质病变存在，也就是与血管机能失调有关的脑部神经突触损坏。
The average intracranial brain volume was significantly smaller in both men and women with Alzheimer's and dementia than in participants with normal cognitive skills, results showed. Also, smaller brain volume was associated with increasing severity of dementia.
结果显示，无论男女，患痴呆症者的平均颅内脑容量都比认知正常者的小得多。此外，脑容量越小，痴呆症越严重。
Brain size didn't differ between individuals carrying a gene mutation associated with Alzheimer's and those without the mutation. Also, there was no association found between white matter lesions and dementia in participants with the largest head size.
携带痴呆症相关基因突变者与未携带者的脑部大小没有区别。脑容量最大的参与者中也没有发现白质病变与痴呆症的关联。
Previous research involving younger people has suggested that larger brains have a reserve capacity that delays age-related disease processes. The latest study is the first to look at brain size and dementia in elderly people, the researchers said.
以往对年龄较小人群的研究表明，容量较大的大脑拥有能够推迟年龄相关疾病进程的备用容量。研究人员说，这次是首次对老年人的脑部大小与痴呆症关联进行研究。
Caveat: CT scans only estimate intracranial brain volume and measurement errors are possible, researchers said.
注意：研究人员说，CT扫描只能大概测量颅内脑容量，可能会存在测量误差。
Title: Head size may modify the impact of white matter lesions on dementia
论文标题：《头部大小可能会改变白质病变对痴呆症的影响》（Head size may modify the impact of white matter lesions on dementia）
Ann Lukits
- journal [´dʒə:nəl]
n.日记；日报；杂志 (初中英语单词) - normal [´nɔ:məl] a.正规的 n.正常状态 (初中英语单词)
- measure [´meʒə] n.量度；范围 vt.测量 (初中英语单词)
- volume [´vɔlju:m, ´vɑljəm] n.卷；书籍；体积；容量 (初中英语单词)
- differ [´difə] vi.不同；有差别 (初中英语单词)
- research [ri´sə:tʃ] n.&vi.调查；探究；研究 (初中英语单词)
- capacity [kə´pæsiti] n.容量；智能；能力 (初中英语单词)
- estimate [´estimət, ´estimeit] n.估计；评价 vt.估价 (初中英语单词)
- measurement [´meʒəmənt] n.测量；尺寸；宽度 (初中英语单词)
- swedish [´swi:diʃ] a.瑞典人 n.瑞典语 (英语四级单词)
- severity [si´veriti] n.严厉；严重；苛刻 (英语四级单词)
- elderly [´eldəli] a. 较老的，年长的 (英语四级单词)
- impact [´impækt] n.影响，作用；冲击 (英语六级单词)
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